America, 1899. The end of the Wild West era has begun as lawmen hunt down the last remaining outlaw gangs. After a robbery goes badly wrong in the western town of Blackwater, Arthur Morgan and the Van der Linde gang are forced to flee. With federal agents and the best bounty hunters in the nation massing on their heels, the gang must rob, steal, and fight their way across the rugged heartland of America in order to survive.